Updated September 25, 2026. Fact-checked against veterinary sources; review by a licensed veterinarian is in progress. See our editorial policy.
Quick answer: Older cats often live with untreated arthritis pain. Safe options include frunevetmab (Solensia), a monthly injection FDA-approved for arthritis pain in cats, and anti-inflammatory drugs such as robenacoxib or meloxicam used carefully under a vet’s supervision, especially in cats with kidney disease. Gabapentin and buprenorphine are also used. Never give human pain relievers: acetaminophen is deadly to cats, and aspirin and ibuprofen are dangerous.
Options vets use
- Frunevetmab (Solensia): monthly injection targeting nerve growth factor
- NSAIDs approved for cats, with label limits and kidney monitoring
- Gabapentin: for chronic pain, and also used to reduce stress before vet visits
- Buprenorphine: an opioid for short-term or severe pain
Monitoring
- Bloodwork to check kidney function before and during NSAID use
- Watch for vomiting, poor appetite, or changes in thirst
- Report sleepiness or wobbliness with gabapentin
Non-drug help
- Weight management
- Ramps, steps, and low-sided litter boxes
- Warm, soft bedding
- Gentle play
Never give
- Acetaminophen (Tylenol)
- Ibuprofen or naproxen
- Aspirin, unless specifically prescribed
- Dog pain medications
More: signs of pain in older cats.
Sources
- US FDA: Approval of Solensia (frunevetmab) for osteoarthritis pain in cats. 2022
- Monteiro BP, et al. 2022 WSAVA guidelines for the recognition, assessment and treatment of pain. J Small Anim Pract. 2022
- Sparkes AH, et al. ISFM and AAFP consensus guidelines: long-term use of NSAIDs in cats. J Feline Med Surg. 2010
This article is for general education and is not a substitute for care from your own veterinarian. Learn about The Pet Vet and our editorial policy.