Updated September 25, 2026. Fact-checked against veterinary sources; review by a licensed veterinarian is in progress. See our editorial policy.
Quick answer: Shaker syndrome, also called steroid-responsive or idiopathic generalized tremor syndrome, causes sudden, whole-body tremors in young to middle-aged dogs. It was first described in small white breeds like Maltese and West Highland White Terriers, but can affect any dog. Dogs usually stay alert. It’s thought to be an immune-related inflammation of the nervous system and typically improves within days to weeks of steroid treatment. Toxins and other causes of tremors must be ruled out first.
Signs
- Fine to severe whole-body tremors that worsen with excitement or stress
- Head bobbing
- Wobbly walking in some dogs
- Rapid eye movements in some dogs
- Usually alert and aware
Other causes of tremors to rule out
- Toxins, such as moldy food, snail bait, chocolate, or medications
- Low blood sugar or low calcium
- Liver disease
- Pain, fear, or cold
Tremors after possible toxin exposure are an emergency. Call your vet or a pet poison hotline.
Diagnosis
- Neurological exam
- Bloodwork
- Sometimes spinal fluid testing or MRI
Treatment
- Corticosteroids, tapered over weeks to months
- Sometimes a short course of anti-anxiety medication
- Most dogs improve within a week; some relapse and need re-treatment
Sources
- Merck Veterinary Manual: Tremors in dogs
- Wagner SO, Podell M, Fenner WR. Generalized tremors in dogs: 24 cases (1984–1995). JAVMA. 1997
This article is for general education and is not a substitute for care from your own veterinarian. Learn about The Pet Vet and our editorial policy.