Updated September 25, 2026. Fact-checked against veterinary sources; review by a licensed veterinarian is in progress. See our editorial policy.
Quick answer: Human medications are among the most common causes of dog poisoning. The most dangerous include NSAIDs (ibuprofen, naproxen), acetaminophen, ADHD medications, antidepressants, heart and blood pressure drugs, sleep aids, and decongestants. Never give your dog a human medication unless your vet prescribes it, and call for help right away if your dog swallows any: ASPCA Animal Poison Control Center (888) 426-4435 or Pet Poison Helpline (855) 764-7661 (fees apply).
This guide doesn’t give doses. Even “safe” human medications can be dangerous at the wrong dose.
High-risk medications
- Ibuprofen and naproxen: stomach ulcers and kidney failure
- Acetaminophen: liver damage and red blood cell damage
- Aspirin: stomach bleeding
- ADHD medications: agitation, high heart rate, high temperature, seizures
- Antidepressants: agitation, tremors, seizures
- Beta blockers and calcium channel blockers: dangerously low heart rate and blood pressure
- Sleep aids and benzodiazepines
- Decongestants (pseudoephedrine, phenylephrine)
- Diabetes medications
- Topical products: creams with fluorouracil, nicotine patches, and others
Hidden danger: xylitol
Some liquid medications, chewables, and gummies contain xylitol, which is highly toxic to dogs.
If your dog swallows medication
- Count what’s missing
- Call your vet or a poison hotline
- Bring the bottle
More: pet medication overdose.
Sources
- ASPCA Animal Poison Control Center: Top pet toxins
- Pet Poison Helpline: Poison list
- Merck Veterinary Manual: Toxicology overview in small animals
This article is for general education and is not a substitute for care from your own veterinarian. Learn about The Pet Vet and our editorial policy.