Updated October 14, 2026. Fact-checked against veterinary sources; review by a licensed veterinarian is in progress. See our editorial policy.
Quick answer: Dasuquin with MSM is a joint supplement for dogs made by Nutramax that combines glucosamine, chondroitin sulfate, avocado/soybean unsaponifiables (ASU), and MSM. Evidence for joint supplements in dogs is mixed: some dogs seem to benefit, but studies are inconsistent. For dogs with arthritis, weight management, omega-3 fatty acids, and veterinary pain medications have stronger evidence. A supplement can be a reasonable add-on, not a replacement.
What’s in it
- Glucosamine and chondroitin: cartilage building blocks
- ASU: plant extract studied for joint health
- MSM: a sulfur compound marketed for joint comfort
What the evidence shows
- Glucosamine and chondroitin: mixed results in dogs
- Omega-3 fatty acids: better evidence for improving arthritis signs
- Veterinary NSAIDs and newer injectable options: strongest evidence for pain relief
Alternatives and add-ons
- Omega-3 fish oil or a therapeutic joint diet
- Weight loss for overweight dogs
- Pain medication from your vet
- Physical rehabilitation
- Other joint supplements with the NASC quality seal
Tips
- Give it for 4–6 weeks before judging results
- Tell your vet about all supplements
- Check calories and ingredients if your dog has allergies or is on a diet
More: arthritis treatment options.
Sources
- Nutramax Laboratories: Dasuquin with MSM product information
- Mosley C, et al. 2022 AAHA Pain Management Guidelines for Dogs and Cats. J Am Anim Hosp Assoc. 2022
- Roush JK, et al. Multicenter veterinary practice assessment of the effects of omega-3 fatty acids on osteoarthritis in dogs. JAVMA. 2010
This article is for general education and is not a substitute for care from your own veterinarian. Learn about The Pet Vet and our editorial policy.